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Research
Interests:
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Bioinformatics, computational systems biology, Intelligent computing, information visualization, advanced image analysis, cellular and molecular imaging, and image guided radiation therapy.
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Current
or Recent Research Sponsors:
Title |
Endocrine Therapy of Breast Cancer |
Agency |
DOD/CDMRP |
Project |
N BC030280 , Clarke (PI) (5/16/2004 – 5/15/2008) |
Role |
Co-PI at Virginia Tech |
Title |
Improved Diagnostics of the Muscular Dystrophies |
Agency |
NIH/NINDS |
Project |
NS29525, Hoffman (PI) (3/1/2005-2/28/2010) |
Role |
Co-PI at Virginia Tech |
Title |
Computational Decomposition of Composite Molecular Signatures |
Agency |
NIH/NIBIB |
Project |
EB000830, Wang (PI) (9/1/03-8/31/08) |
Role |
Co-PI |
Title |
Polarization Imaging Apparatus for Cell and Tissue Imaging and Diagnostics
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Agency |
NASA |
Project |
NNJ05JC13C, Zou (PI) (2/20/2005-7/16/08) |
Role |
Co-PI at Virginia Tech |
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Teaching
Interests/Courses:
Visual intelligence & computer vision, pattern recognition, bioinformatics, computational systems biology, machine learning, digital image processing, information visualization, computer graphics, multimedia processing, and information retrieval .
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Publications/Reports:
R. Srikanchana, J. Xuan, M. Freedman, C. Nguyen and Y. Wang, “Non-Rigid Image Registration by Neural Computation,” Journal of VLSI Signal Processing Systems, vol. 37, no. 2-3, pp. 237-246 , 2004.
J. Xuan, Y. Wang, Q. Zheng and T. Adali, “ Discontinuity-Embedded Deformable Models for Surface Reconstruction From Range Images,” IEEE Signal Processing Letters, vol. 12, no. 12, pp. 805-808, 2005.
J. Xuan , Y. Wang, M. Freedman, T. Adali and P. G. Shields, “Nonrigid Medical Image Registration by Deformable Sheet-Curve Models,” International Journal of Biomedical Imaging, vol. 2006, Article ID 73430, pp. 1-9, 2006.
M. Bakay, G. Melcon, Z. Wang, L. Schiltz, J. Xuan, et al., Y. Wang and E. P. Hoffman, “Nuclear Envelope Dystrophies Show A Transcriptional Fingerprint Suggesting Disruption of Rb-MyoD Pathways in Muscle Regeneration ,” Brain, vol. 129, no. 4, pp. 996-1013, 2006.
Y. Wang, J. Xuan, R. Srikanchana and P. L. Choyke, “Modeling and Reconstruction of Mixed Functional and Molecular Patterns,”International Journal of Biomedical Imaging, vol. 2006, Article ID 29707, pp. 1-9, 2006.
Z. Wang, Y. Wang, J. Xuan, Y. Dong, M. Bakay, Y. Feng, R. Clarke and E. P. Hoffman, “Optimized Multilayer Perceptrons for Molecular Classification and Diagnosis Using Genomic Data,” Bioinformatics, vol. 22, no. 6, pp. 755-761, 2006.
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Education:
Ph.D., Electrical Engineering & Computer Science, University of Maryland, 1997
Ph.D., Electrical Engineering, University of Zhejiang, 1991
M.S., Electrical Engineering, University of Zhejiang, 1988
B.S., Electrical Engineering, University of Zhejiang, 1985
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Professional
affiliations:
Computational Bioinformatics and Bioimaging Laboratory, Virginia Tech
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